$783,00
Human weight: no more than 170 kg
Form: powder
Ingredients: aconite, flavoring, sugar
Country of origin: Indonesia
Active ingredient: aconite
Concentration: 47%
Weight: 1 g
C34H47NO11 is an alkaloid from plants of the genus Aconitum (wrestler, wolfsbane, and skullcap).
It is found primarily in tubers and leaves.
In small doses, it was previously used in medicine as an analgesic and antirheumatic agent, but its use was discontinued due to its extreme toxicity.
It is sometimes included in homeopathic preparations, which poses a serious risk in case of overdose.
Aconitine is a potent neuro- and cardiotoxin that activates voltage-gated sodium channels, causing them to remain open for extended periods.
This leads to continuous depolarization of neuronal and cardiomyocyte membranes, conduction disturbances, and fibrillation.
It is highly toxic when taken orally, inhaled, and even through skin contact.
There is no antidote.
Lethal Dose:
For humans, the lethal dose is 1-2 mg of pure alkaloid or 3-5 g of aconite root.
Just a few drops of the tincture can cause death.
Time to Death:
Oral poisoning: 1 to 6 hours.
Skin contact: up to 24 hours.
Death occurs from respiratory paralysis or ventricular fibrillation.
Signs of poisoning:
• Numbness and tingling in the mouth and face
• Burning sensation along the esophagus, abdominal pain, nausea, vomiting
• Numbness in the extremities, a crawling sensation
• Irregular heartbeat, drop in blood pressure
• Convulsions, loss of consciousness, respiratory arrest
• A characteristic symptom is a feeling of coldness and sweating while remaining conscious
It is found in gastric contents, blood, liver, kidneys, heart, and brain.
Methods: HPLC, TLC, GC-MS, spectrophotometry.
Traces persist in tissues for up to 2 weeks after death.
Morphologically: pulmonary edema, cardiac and mucous congestion, dark, liquid blood.
Store in a tightly sealed container.
Avoid contact with skin and mucous membranes.
Shelf life: up to 3 years.
